Phase 3 Oesophageal Cancer Trial, Recruiting NCT05919030 Sponsor: Renmin Hospital of Wuhan University Condition: Oesophageal Cancer
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Phase 3 Oesophageal Cancer Trial, Recruiting

NCT05919030
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a specific type of oesophageal (food pipe) cancer called squamous cell carcinoma, confirmed through laboratory testing of a tissue sample.
  • People whose cancer cannot be removed by surgery and has either spread to other parts of the body, come back after previous treatment, or is too advanced to treat.
  • People whose cancer is not suitable for potentially curative treatments such as a combination of chemotherapy with radiation therapy, or surgery.
  • People whose tumour shows low levels of a particular protein marker called PD-L1 (specifically, a score below 10).
  • People who have not yet received any systemic (whole-body) drug treatment, such as chemotherapy, for their advanced or metastatic disease.
  • People who are in good general health, able to carry out everyday activities with little or no limitation (as rated by a standard medical scale called ECOG, at level 0 or 1).
  • People who have at least one tumour that can be clearly measured on a CT or MRI scan, with that scan taken within 28 days before joining the trial.
  • People whose liver, kidneys, and bone marrow are functioning at an adequate level.

Who may not be able to join:

  • People who have cancer that has spread to the brain or spinal cord and is causing symptoms or needs treatment.
  • People who have an active autoimmune disease (a condition where the immune system attacks the body's own tissues).
  • People who have a serious uncontrolled medical condition or an active infection.
  • People who have a known history of HIV or AIDS.
  • People who have tested positive for hepatitis B or C, showing an active or ongoing infection.
  • People who have previously been treated with certain immune-based therapies that target specific pathways involved in immune system regulation (confirm with trial site for the full list of relevant medications).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +86 15327122084

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Renmin Hospital of Wuhan University
Registry
ClinicalTrials.gov
Start date
1 July 2023
Est. completion
1 July 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Progression-Free Survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov