Phase 4 Motor Neurone Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with ALS (Amyotrophic Lateral Sclerosis), either inherited or non-inherited, confirmed using standard medical guidelines
• You are between 18 and 80 years old
• Your ALS symptoms started no more than 18 months ago
• Your ALS function rating score is at or above a certain level, meaning your daily abilities (including breathing) are still relatively preserved (confirm with trial site)
• Your lung capacity is at least 70% of what would be expected for someone of your age, height, and gender
• A brain activity (EEG) analysis using AI shows a specific pattern related to low mood or depression (confirm with trial site)
• If you are able to have children (male or female), you agree to use an accepted form of contraception during the trial
• You are willing to take part voluntarily and sign a consent form

Who may not be able to join:

• You have dementia, or a serious brain, mental health, or other medical condition that is poorly controlled or could affect the trial
• You are currently pregnant or breastfeeding
• You have a history of attempted suicide
• You have another neurological condition with symptoms similar to ALS, such as spine-related nerve problems or dementia
• You have had spinal surgery after your ALS diagnosis
• Your liver or kidney function tests fall outside acceptable ranges (confirm with trial site)
• You have a known allergy to the medication being tested in this trial
• You have taken part in another clinical trial within the last 3 months
• The trial doctor has another reason they feel you are not suitable for this study

⚠️ Important: Always verify eligibility with the trial site directly before applying.