Glaucoma Trial, Recruiting NCT05924477 Sponsor: University of Pennsylvania Condition: Glaucoma
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Glaucoma Trial, Recruiting

NCT05924477
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have glaucoma that is not well controlled with medication and who are scheduled to have a glaucoma drainage device (a small implant to help drain fluid from the eye) placed, either alone or combined with cataract surgery
  • People whose eye anatomy is suitable for the drainage device to be placed in specific positions inside the eye (confirm with trial site)
  • People aged 18 years or older

Who may not be able to join:

  • People who have a pre-existing eye condition affecting the clear front layer of the eye (cornea), or who have previously had a corneal transplant
  • People who currently have, or have previously had, a specific implant called a Cypass Micro-Stent
  • People who had a previous glaucoma drainage device, Xen Gel Stent, or Preserflo MicroShunt removed less than 6 months before the planned surgery
  • People who currently have a glaucoma drainage device, Xen Gel Stent, or Preserflo MicroShunt already in place
  • People who have had certain types of glaucoma surgery (trabeculectomy or minimally invasive glaucoma surgery) within the past 6 months
  • People who have a certain type of artificial lens already implanted in the front chamber of the eye
  • People who have certain specific eye or health conditions, including nanophthalmos (a very small eye), uncontrolled eye inflammation (uveitis), silicone oil in the eye, Sturge-Weber syndrome, or other conditions that raise pressure in the veins around the eye
  • People who are unwilling or unable to give consent, who would not accept being randomly assigned to a treatment group, or who are unable to attend the required follow-up visits
  • People who have no light perception in the eye being studied, or whose other eye has very poor vision (below a certain threshold)
  • People who need glaucoma surgery combined with other eye procedures such as a corneal transplant or retinal surgery, or who are expected to need additional eye surgery

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ying Han, MD, PhD, University of California, San Francisco

Phone: 215-615-1514

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
11 July 2023
Est. completion
1 December 2026

Where this trial is recruiting

🇨🇦 Canada 🇺🇸 United States

Primary endpoints

Central endothelial cell loss (ECL) from baseline

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov