Alzheimer's Disease Trial, Recruiting NCT05925621 Sponsor: Beth Israel Deaconess Medical Center Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT05925621
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been clinically identified as having mild cognitive impairment or early-stage Alzheimer's disease dementia.
  • People who show signs of cognitive impairment on neuropsychological testing.
  • People whose cognitive impairment has not reached the moderate stage of dementia, based on testing or a doctor's assessment.
  • People whose brain scan (amyloid PET) or spinal fluid analysis (CSF) shows results consistent with Alzheimer's disease.
  • People with a positive amyloid PET brain scan, or spinal fluid results showing specific protein levels linked to Alzheimer's disease (confirm with trial site for exact values).
  • People who have had a 3T MRI brain scan within the past 6 months.
  • People who have a care partner (such as a family member or close friend who supports them).
  • People who are under the care of an appropriate amyloid clinic at BI-Lahey.
  • People who are on a stable, unchanged medication routine.

Who may not be able to join:

  • People who have had a stroke or a suspected mini-stroke (TIA) in the past year.
  • People who are pregnant.
  • People who have an active autoimmune or immune system disease.
  • People who are currently taking immunosuppressant medications, immunoglobulins, or monoclonal antibody treatments.
  • People who have a bleeding disorder with certain abnormal blood clotting results (confirm specific values with trial site).
  • People who are currently taking blood-thinning medications such as warfarin, heparin, or direct oral anticoagulants (DOACs).
  • People who are taking two different antiplatelet (anti-clotting) medications at the same time.
  • People whose cognitive impairment or dementia is caused by something other than Alzheimer's disease.
  • People who carry two copies of the ApoE e4 gene variant (known as ApoE e4 homozygotes).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: (617) 667-4074

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
16 July 2023
Est. completion
1 June 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To Determine Whether Anti-Amyloid Mabs Slow Cognitive And Functional Decline; To Identify Any Associations Between Side Effects And Patient Characteristics; To Establish The Time Course Of Clinical Benefits

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov