Vasculitis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Children and teenagers between 1 and 18 years old
• Patients who have been diagnosed with HSP (Henoch-Schönlein Purpura, a condition that causes a skin rash and can affect the joints, gut, and kidneys)
• Patients whose skin rash from HSP is severe (widespread and dense) and has not gone away — or new rashes keep appearing — even after being treated with standard medicines like antibiotics, antihistamines, calcium, and steroids for at least 5 days, and the rash has come back more than 3 times during their hospital stay
• A parent or guardian is willing to agree to the treatment and sign a consent form

Who may not be able to join:

• Anyone who is allergic to the drug leflunomide
• Patients who have another serious underlying illness, such as cancer, heart failure, liver or kidney failure, a weakened immune system, a severe infection, or who have had an organ transplant or need urgent surgery
• Patients who also have other diseases affecting the digestive system
• Anyone who has previously taken a drug called flumiphene as part of a clinical trial (confirm with trial site)
• Patients whose purpura (rash) is caused by a medication, an infection, or another autoimmune disease — rather than HSP itself
• Anyone the researchers feel, for any other reason, should not take part in the study (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.