Asthma Trial, Recruiting NCT05945355 Sponsor: Duke University Condition: Asthma
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Asthma Trial, Recruiting

NCT05945355
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Children and teenagers between 6 and 17 years old
  • People who have been diagnosed with asthma by a doctor
  • People whose asthma currently requires 2 or more regular (controller) medications to manage, which typically indicates moderate to severe persistent asthma
  • People who are either in a normal weight range (BMI between the 5th and 84th percentile for their age) or are considered obese (BMI at or above the 95th percentile but below 170% of the 95th percentile, based on CDC growth charts)

Who may not be able to join:

  • People whose asthma control test (ACT) score is below 17, indicating poorly controlled asthma
  • People who have ever needed a breathing tube (been placed on a ventilator) due to an asthma attack
  • People whose lung function test result (FEV1) is below 50% of what would be expected for someone of their age and size
  • People who are currently pregnant
  • People whose parent or legal guardian is unable to give consent in either English or Spanish
  • People who have another serious ongoing illness that, in the treating doctor's judgement, would interfere with taking part in the trial
  • Children younger than 6 years of age

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jason Lang, MD, Duke University

Phone: 9196843364

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
1 August 2024
Est. completion
30 October 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of participants with inspiratory muscle dysfunction in obesity-related versus non-obesity-related asthma; Number of participants with small airway dysfunction in obesity-related versus non-obesity-related asthma

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov