Breast Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For both groups:
- You are 18 years old or older and have been diagnosed with breast cancer that cannot be removed by surgery and/or has spread to other parts of the body, confirmed by a lab test
- Your doctor has decided to start you on one of two treatments: a drug called T-DXd (trastuzumab deruxtecan) or standard chemotherapy
- You are willing and able to sign a consent form to take part in the study
For Group 1 only:
- Your breast cancer has been tested and found to be "HER2-low" (a specific low level of a protein called HER2, confirmed by lab testing)
- You have already received chemotherapy after your cancer spread, OR your cancer came back during or within 6 months of finishing chemotherapy given after surgery
For Group 2 only:
- Your breast cancer has been tested and is hormone receptor positive (meaning it is fuelled by hormones like oestrogen or progesterone)
- Your breast cancer is either "HER2-low" or "HER2-ultralow" (very specific low levels of HER2 protein, confirmed by lab testing)
- You have already received at least one hormone-based therapy after your cancer spread
- You have NOT yet received chemotherapy after your cancer spread
Who may not be able to join:
- You are currently pregnant or breastfeeding
- You are currently taking part in, or have recently taken part in, another clinical trial where neither you nor your doctor knows which treatment you received (a "blinded" study)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Real World Time to Next Treatment (rwTTNT1) in Participants With Unresectable and/or Metastatic Breast Cancer
Can't join this trial?
Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.