Schizophrenia Trial, Recruiting NCT05956951 Sponsor: Fabio Ferrarelli Condition: Schizophrenia
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Schizophrenia Trial, Recruiting

NCT05956951
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people with early schizophrenia:

  • People aged 18 to 40 years old
  • People with a diagnosed schizophrenia-related condition (schizophrenia, schizophreniform disorder, or schizoaffective disorder) that was not caused by drug use, and who have not had a previously recorded psychotic episode
  • People whose psychosis began no more than 5 years ago, based on reported symptoms or treatment history
  • People who have taken antipsychotic medications for a total of 5 years or less in their lifetime

For healthy volunteers:

  • People aged 18 to 40 years old
  • People with no history of any psychiatric condition at any point in their life
  • People with no close family member (parent, sibling, or child) who has had schizophrenia or a mood disorder involving psychosis

Who may not be able to join:

For everyone:

  • People with an intellectual disability
  • People who have had a significant head injury
  • People with a medical condition that affects how the brain works or is structured
  • People who are currently pregnant or who have given birth or had a miscarriage within the past 6 weeks
  • People with a significant neurological condition, such as epilepsy or a seizure disorder
  • People who are not able to give informed consent to take part
  • People with a current or past diagnosis of dependence on alcohol or any mind-altering substance
  • People who have used substances other than cannabis or alcohol in the past year

Additionally, for people with early schizophrenia:

  • People whose psychotic illness appears to be directly related to substance use or a head injury

Additionally, for healthy volunteers:

  • People who regularly have trouble falling or staying asleep on more than half the nights of a typical week
  • People who have been diagnosed with sleep apnea or restless leg syndrome
  • People who sleep less than 5 hours or more than 10 hours per night on average

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Fabio Ferrarelli, MD,PhD, University of Pittsbrugh

Phone: 412-246-6114

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Fabio Ferrarelli
Registry
ClinicalTrials.gov
Start date
20 July 2023
Est. completion
1 June 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Deficits in sleep spindle and slow wave density in early-course schizophrenia patients (EC-SCZ).; Deficits in sleep spindle and slow wave duration in early-course schizophrenia patients (EC-SCZ).; Deficits in sleep spindle and slow wave amplitude in early-course schizophrenia patients (EC-SCZ).; Improvement in sleep spindle and slow wave density.; Improvement in sleep spindle and slow wave duration.; Improvement in sleep spindle and slow wave amplitude.; Relationship between spindle and slow wave deficits and memory consolidation.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov