Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years of age or older
- You are willing and able to sign a consent form agreeing to take part
- You have been diagnosed with a type of irregular heartbeat called atrial fibrillation (AF) — either all the time, most of the time, or coming and going — whether known before or found during a recent hospital stay
- You have had a stroke caused by a blood clot within the last 3 months, and had symptoms from it
- You were already taking blood-thinning medication (anticoagulants) at the time your stroke happened, and had not stopped taking it for more than 48 hours beforehand
- You are currently taking or plan to take a type of blood thinner called a DOAC (a modern oral anticoagulant tablet) long-term
Who may not be able to join:
- You cannot safely take DOAC blood-thinning medication for medical reasons
- Your doctor believes you are not likely to live for more than 1 year
- Your stroke was caused by a narrowed artery on the same side as the stroke, was a very small "lacunar" stroke, or was caused by another specific identified condition such as a heart valve infection, inflamed blood vessels, or certain rare brain conditions
- You have previously had a procedure to close a small natural opening or hole in the wall between the upper chambers of your heart
- You have a heart condition caused by rheumatic disease (a type of inflammatory illness)
- You have a serious heart valve problem that needs treatment (such as severely narrowed or leaking aortic or mitral valves)
- You have a condition that makes it unsafe to perform a procedure using a tube passed down your throat (for example, swollen veins in your food pipe, a narrowed food pipe, or a history of cancer of the food pipe)
- You have had a heart or non-heart-related surgical procedure in the 30 days before joining the trial
- You are already taking part in another study involving a heart device or a treatment to prevent a second stroke
- Your heart's main pumping chamber is working at less than 30% of its normal capacity
- Your kidneys are severely impaired to a level that makes certain DOAC medications unsafe for you (confirm with trial site for exact kidney function thresholds)
- You have a thickened heart muscle condition called hypertrophic cardiomyopathy
- You have a tumour inside your heart
- You have a blood clot inside one of your heart's pumping chambers
- Your heart is in a state of sudden severe failure at the time of joining
- The small pouch on the upper left chamber of your heart (called the left atrial appendage) has already been closed off or surgically tied
- A blood clot found in that pouch has not gone away after 4 weeks of blood-thinning treatment (confirm with trial site)
- You are currently pregnant or breastfeeding (a pregnancy test will be required for women who could become pregnant)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Lorenz Räber, Prof., MD, Cardiovascular Center, Inselspital Bern
Phone: +41316320929
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Composite of recurrent ischemic stroke, systemic embolism, or cardiovascular death (whatever comes first).
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.