Stroke Trial, Recruiting NCT05999318 Sponsor: Changping Laboratory Condition: Stroke
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Stroke Trial, Recruiting

NCT05999318
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 35 and 75 years old (including those who are exactly 35 or 75).
  • People who have been diagnosed with an acute ischemic stroke (a stroke caused by a blocked blood vessel) affecting the left side of the brain, where the stroke occurred at least 15 days ago but no more than 3 months ago.
  • People whose stroke has caused a language problem called aphasia, confirmed by a specific Chinese language test (the Chinese version of the Western Aphasia Battery), with a score below 93.8.
  • People who are experiencing their first-ever stroke.
  • People whose language ability was normal before their stroke, whose native language is Chinese, and who have had at least 6 years of formal education.
  • People who understand what the trial involves and have signed a consent form agreeing to take part.

Who may not be able to join:

  • People with severe difficulty speaking clearly due to muscle or movement problems (severe dysarthria), based on a specific score on a standard stroke scale.
  • People whose aphasia (language difficulty) was caused by something other than a single-sided stroke — for example, strokes on both sides of the brain, a brain tumour, a head injury, Parkinson's disease, or motor neuron disease.
  • People who have an implanted electronic device such as a heart pacemaker or cochlear implant, any metal objects in the body, or who cannot have an MRI scan for any reason (such as claustrophobia), or who cannot receive a type of brain stimulation treatment called TMS.
  • People with a history of epilepsy (seizures).
  • People with serious, uncontrolled illness affecting the heart, lungs, liver, kidneys, or other major organs, as confirmed by medical tests.
  • People who have a reduced level of consciousness, based on a specific score on a standard stroke scale.
  • People with very high blood pressure that is dangerously difficult to control (malignant hypertension).
  • People with a serious illness such as cancer, where life expectancy is estimated to be less than one year.
  • People with severe hearing loss, severe vision problems, severe difficulties with memory or thinking, or who are otherwise unable to participate in the trial activities.
  • People with severe depression, severe anxiety, or another diagnosed mental health condition that would prevent them from completing the trial.
  • People who have received brain stimulation treatments (such as TMS or transcranial electrical stimulation) within the 3 months before joining the trial.
  • People with a history of alcohol dependence, drug misuse, or other substance misuse.
  • People whom the research team determines are unsuitable for the trial for any other medical reason.
  • People who would be unable to attend all required follow-up visits due to where they live or other practical reasons.
  • Women who are currently pregnant, breastfeeding, or who are planning to become pregnant or may become pregnant during the trial.
  • People who are currently enrolled in another clinical trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Hesheng Liu, PhD, Changping Laboratory

Phone: 010-80726688

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Changping Laboratory
Registry
ClinicalTrials.gov
Start date
7 November 2023
Est. completion
20 August 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Change in the Western Aphasia Battery scores

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov