Peripheral Arterial Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are able to give written, informed consent
- People who have a confirmed diagnosis of blocked or narrowed arteries in the lower limbs, based on blood pressure measurements taken at the ankle and arm, and/or medical imaging of the arteries
- People who have a history of chronic claudication (ongoing leg pain or cramping during walking caused by reduced blood flow)
- People whose blood pressure, cholesterol, and diabetes medications and treatments have been stable and unchanged for at least 6 weeks before joining
Who may not be able to join:
- People who experience pain in their legs while resting, or who have wounds or tissue damage caused by poor blood flow to the legs (known as Fontaine stage III and IV peripheral artery disease)
- People who have recently had a sudden loss of blood flow to a lower limb caused by a blood clot or acute injury
- People whose ability to walk is limited by conditions other than claudication, such as joint or muscle problems, nerve conditions, heart disease, or lung disease
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Iraklis I Pipinos, MD, Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE
Phone: (402) 995-3542
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Distance walked; Energy expenditure; Reactive oxygen species; Protein expression of ROS-related enzymes; Markers of systemic inflammation; Initial and absolute walking distances; Comprehensive mitochondrial respiratory complex function; Mitochondrial dynamics; Mitochondrial reactive oxygen species production
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.