Crohn's Disease and Colitis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must be 18 years of age or older.
• You must be male, or a female who is not currently pregnant or breastfeeding.
• You must have had bowel surgery and then shown signs of Crohn's disease coming back, confirmed by a camera test (endoscopy) done 6 to 24 months after surgery, showing ulcers in the area where your bowel was reconnected.
• In the doctor's opinion, you are able to understand and follow the study requirements.
• You must be willing to sign a consent form agreeing to take part before any study activities begin.

Who may not be able to join:

• You have conditions such as a history of alcohol or substance misuse, or difficulty following medical instructions, that the doctor believes could affect your ability to take part properly.
• You have a health condition that would make one of the possible treatments unsafe for you — for example, severe heart failure, multiple sclerosis, or an active infection (confirm with trial site).
• You have taken part in another clinical trial involving an experimental drug in the last 30 days or longer (confirm with trial site).
• You are currently in, or planning to join, another study involving an experimental treatment.
• You are pregnant, planning to become pregnant, or plan to become pregnant during the study.
• You have previously been diagnosed with pre-cancerous changes (dysplasia) in the colon, unless it was only found in a removed polyp.
• You have had a cancer diagnosis in the 3 years before joining the study, except for a common type of skin cancer (non-melanoma skin cancer).
• You received a biologic therapy (a type of advanced medication) between your surgery and your first camera test after surgery.
• You currently have a gut infection caused by a bacteria called Clostridium difficile — although if you test positive, you may still be able to join if you are successfully treated and test negative within 4 weeks of your screening visit.
• You have a stoma bag and your bowel has not been reconnected internally.
• You have an active abscess or open, draining fistula in the area around your bottom.
• Your liver enzyme levels (ALT or AST) are more than 3 times the normal upper limit based on blood tests at screening.
• You have a condition that increases your risk of bleeding, such as a blood clotting disorder, or you are taking blood-thinning medications.

Important: Always verify eligibility with the trial site directly before applying.