Motor Neurone Disease Trial, Recruiting NCT06021938 Sponsor: Assistance Publique - Hôpitaux de Paris Condition: Motor Neurone Disease
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Motor Neurone Disease Trial, Recruiting

NCT06021938
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years old or older
  • You have been diagnosed with ALS (also known as Lou Gehrig's disease), confirmed using a standard set of medical guidelines called the "revised El Escorial criteria"
  • You have breathing difficulties caused by weakness in your diaphragm (the main breathing muscle), and you have been using a non-invasive breathing support machine (such as a CPAP or BiPAP) for more than one month
  • You receive your care in an outpatient or day hospital setting (meaning you do not stay overnight in hospital for your regular care)
  • You experience persistent shortness of breath at rest, rated 3 or higher on a scale of 0 to 10, while sitting in a semi-upright position
  • Your condition has been stable, meaning you have not had a serious heart, breathing, or neurological crisis that required hospital admission in the past 4 weeks
  • You are willing and able to give written consent to take part in the study
  • You are covered by the French national health insurance system (Social Security)

Who may not be able to join:

  • You have been diagnosed with a neurological condition (such as dementia, Alzheimer's disease, a brain tumour, stroke, or Parkinson's disease), confirmed by a neurological assessment done within the last year
  • You have been diagnosed with a serious mental health condition (such as severe depression or psychosis), or you are currently taking antipsychotic medication
  • You have a fear of heights (acrophobia)
  • You have a fear of enclosed spaces (claustrophobia)
  • You have a sensitivity or aversion to light (photophobia)
  • You have significant hearing loss
  • You have significant problems with your vision
  • You are under a legal guardianship or curatorship arrangement (meaning someone else has been appointed to make decisions on your behalf)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 01 42 16 77 71

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
4 April 2024
Est. completion
4 April 2027

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Evaluate the effect of IVR on respiratory discomfort (A1)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov