Phase 2 Breast Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are 18 years of age or older
- People who were assigned female at birth
- People who have been diagnosed with breast cancer (any stage from I to IV), confirmed by a biopsy
- People who are planned to receive a type of chemotherapy called anthracycline-based chemotherapy (with or without additional targeted therapy for HER2-positive cancer), with at least 2 cycles of this chemotherapy planned
- People whose resting blood pressure reading is 130 mmHg or higher (the top number)
- People who are willing and able to follow the study requirements
- People who own a Bluetooth-enabled mobile device (with wifi or cellular connection) and are willing to use it as part of the study
- (For a specific group in this trial called the CPET cohort): People who are able to complete a baseline exercise test on a bike or treadmill that measures heart and lung function, without showing any concerning signs during the test, and who meet at least one of several specific performance markers during that test (confirm with trial site for full details)
Who may not be able to join:
- People whose kidneys are functioning at a significantly reduced level (a specific blood test result below 30 ml/min/1.73m²)
- People whose arm size is too large to get an accurate blood pressure reading with the devices used in the study
- People for whom blood pressure cannot be accurately measured in either arm — for example, due to swelling in both arms from lymphedema
- People who have had a recent heart attack (within the past 3 months), severe heart failure symptoms, a history of stroke, or a heart transplant
- People who have another medical condition that the study doctor believes would prevent them from safely participating or following the study plan
- (For the CPET cohort only): People who have certain serious heart or lung conditions that make exercise testing unsafe, including but not limited to: a very recent heart attack, unstable chest pain, uncontrolled abnormal heart rhythms, severe heart valve problems, repeated fainting episodes, active heart or lung infections, a recent blood clot in the lungs or legs, a suspected tear in a major blood vessel, uncontrolled asthma, fluid in the lungs, very low oxygen levels at rest, breathing failure, a recent illness or condition that could be made worse by exercise, or a mental condition that makes it difficult to follow instructions during testing
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Anthony Yu, MD, Memorial Sloan Kettering Cancer Center
Phone: 212-639-7932
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
mean change in systolic blood pressure (SBP) from baseline to 12 months
Can't join this trial?
Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.