Breast Cancer Trial, Recruiting NCT06055881 Sponsor: Mayo Clinic Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT06055881
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older.
  • Your breast cancer diagnosis has been confirmed through a tissue sample (biopsy).
  • You have metastatic breast cancer that responded well to your first round of systemic treatment (such as chemotherapy or hormone therapy) for at least 12 months, and now 1 to 3 areas outside the brain are showing signs of growth, while you plan to continue your current treatment.
  • OR, you have metastatic breast cancer that responded well to a second (or later) round of systemic treatment for at least 6 months, and now 1 to 3 areas outside the brain are showing signs of growth.
  • Your general health and ability to carry out daily activities meets a certain standard, meaning you are reasonably active and able to care for yourself (confirm with trial site).
  • If you are a woman who could become pregnant, you have had a negative pregnancy test within 7 days before joining the trial.
  • You are able to fill out questionnaires yourself or with help from someone else.
  • You are willing and able to sign a consent form agreeing to take part.
  • You are willing to return to the trial location for follow-up visits during the study.
  • You are willing to provide blood samples for research purposes.
  • You will be receiving radiation therapy as outlined by the trial's guidelines.

Who may not be able to join:

  • You are male.
  • You are currently pregnant or breastfeeding.
  • You are of childbearing potential but are not willing to use adequate birth control during the trial.
  • Your breast cancer is "triple negative" (meaning it tests negative for ER, PR, and HER2 receptors).
  • You currently have another active cancer.
  • You have more than 3 areas outside the brain where your cancer is growing.
  • You have active, unstable cancer in the brain or central nervous system — though if your brain lesions have been treated, are stable, and you have not needed steroid medications for at least 4 weeks, you may still be eligible (confirm with trial site).
  • You have an active connective tissue disease (such as lupus or scleroderma) that your medical team believes could put you at higher risk of serious side effects from treatment.
  • You have had previous radiation treatment in an area that overlaps with where new radiation would be needed, and your radiation doctor does not consider it safe to treat those areas again.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 June 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
23 October 2023
Est. completion
1 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Freedom from a change in systemic therapy (FCST) - overall

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov