Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 or older who are able to give their own consent to participate
- People who have been diagnosed with a type of irregular heartbeat called atrial fibrillation or atrial flutter (which comes and goes, is ongoing, or is permanent) and who are not caused by a heart valve problem, and who have a higher-than-average risk of stroke based on a scoring system called CHA2DS2-VASc (a score of 2 or more for men, or 3 or more for women)
- People whose treating doctor has determined they are not suitable for long-term blood-thinning medication taken by mouth
- People whose treating doctor has assessed them as suitable for a minimally invasive procedure to close off a small pouch in the heart called the left atrial appendage (LAA)
- People who are able to follow the required medication plan after the heart procedure
- People who have provided written agreement to take part in the trial
- People whose heart anatomy is compatible with either of the two specific devices being studied in this trial (both devices must be suitable based on the heart's shape and size)
- Women who could become pregnant must have a negative pregnancy test before joining and agree to use reliable contraception throughout the study
Who may not be able to join:
- People who need long-term blood-thinning medication for a reason other than atrial fibrillation, such as a blood clot in the lungs or a mechanical heart valve
- People whose left atrial appendage (the heart pouch targeted in this procedure) has already been closed off or surgically tied
- People with a known allergy or sensitivity to any materials used in the devices or the required medications
- People who have previously had a repair or a device implanted to close a hole between the upper chambers of the heart (called an atrial septal defect)
- People with an active heart infection or another infection that has spread bacteria into the bloodstream
- People with significant narrowing of the arteries in the neck causing symptoms
- People already taking part in another clinical trial that could affect the results of this one
- People who are unable to follow or complete the trial requirements for any reason
- People found on heart imaging (ultrasound) to have a blood clot inside the heart
- People found on heart imaging to have a tumour inside the heart
- People found on heart imaging to have a significant fluid build-up around the heart
- People found on heart imaging to have significant narrowing of the mitral heart valve
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Michael Joner, MD, Klinik für Herz- und Kreilauferkankungen, Deutsches Herzzentrum München
Phone: +4989-1218-2869
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
PDL size after 3 months
Can't join this trial?
Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.