Oesophageal Cancer Trial, Recruiting NCT06071845 Sponsor: Mayo Clinic Condition: Oesophageal Cancer
Back to Oesophageal Cancer

Oesophageal Cancer Trial, Recruiting

NCT06071845
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

As a "case" participant (people with known or suspected Barrett's esophagus):

  • People between 18 and 90 years old
  • People who have a Barrett's esophagus segment of at least 1cm as seen during a scope procedure, or a note of suspected Barrett's esophagus in their medical records
  • People whose tissue sample results show a specific type of cell change in the esophagus (with or without pre-cancerous changes), or who have suspected Barrett's esophagus noted in their medical records
  • People who are already scheduled for a clinically necessary scope procedure

As a "control" participant (people without known Barrett's esophagus):

  • People who are already scheduled for a clinically necessary diagnostic scope procedure

Who may not be able to join:

  • People who are pregnant or breastfeeding
  • People who are unable to give their own consent to participate
  • People who have difficulty swallowing that has not yet been medically investigated
  • People with a history of eosinophilic esophagitis or achalasia (specific esophageal conditions)
  • People currently taking blood-thinning medications such as Coumadin or Warfarin
  • People taking antiplatelet medications such as Clopidogrel, unless that medication has been stopped three to five days before the study procedure
  • People taking certain other blood-thinning medications (including Dabigatran, rivaroxaban, apixaban, or edoxaban), unless stopped three to five days before the study procedure
  • People with a history of enlarged veins in the esophagus or stomach (varices), or liver cirrhosis
  • People who have had surgical removal of part of the esophagus due to esophageal cancer
  • People with bleeding disorders, whether present from birth or developed later in life
  • People with a history of a specific type of pre-cancerous change in the esophagus called squamous dysplasia
  • People who have had cancer of the pancreas, bile duct, stomach, or nearby areas within the past 5 years
  • People who have received chemotherapy or radiation therapy to treat cancer of the esophagus or the chest area

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Prasad G. Iyer, MD, Mayo Clinic in Rochester

Phone: 855-776-0015

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
16 October 2023
Est. completion
1 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

DNA yield from esophageal cytology samples collected with the Cytosponge device; Accuracy of the Oncoguard Esophagus (OGE) test

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov