Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 21 to 85 years, both male and female
• People who have had their first-ever stroke (either a blocked blood vessel or a bleed in the brain), confirmed by a specialist doctor or brain scan
• People who are more than 16 weeks past their stroke
• People whose stroke has caused weakness on one side of the body in a pattern typical of stroke
• People with at least some ability to lift the shoulder and bend the elbow (at a certain minimum strength level, confirm with trial site)
• People with varying levels of weakness in the fingers and thumb of the affected hand (confirm with trial site for exact range)
• People whose wrist and hand movement score falls below a certain level on a standard stroke assessment (confirm with trial site)
• People with limited or no muscle stiffness in the thumb, index, and middle fingers
• People who can feel a pin-prick sensation in their thumb and index finger
• People whose hand size falls within a specific range (170–200mm long and 75–85mm wide) that fits the robotic glove used in the trial
• People whose brain signals are compatible with a brain-computer interface (BCI) device, as assessed by a standard screening test
• People who can understand simple instructions and score above a certain level on a basic memory and thinking test
• People who are able to give their own informed consent to participate

Note: People whose brain signals are not compatible with the BCI device may still be considered for a different part of the trial (confirm with trial site).

Who may not be able to join:

• People who have had more than one stroke
• People diagnosed with a brain or nerve condition that gets worse over time, such as Parkinson's disease, dementia, or ALS
• People with unstable or serious medical or neurological conditions, or a life expectancy of less than 6 months
• People on dialysis due to kidney failure
• People with severe heart failure
• People with a condition where blood pressure drops significantly when standing up
• People with a history of uncontrolled serious infections
• People who have had an epileptic seizure within 3 months of the study consent date
• People with skin conditions on the hand or arm that could be made worse by wearing a robotic glove, such as open wounds, ulcers, eczema, or active skin infections
• People who are unable to sit upright for at least 90 minutes (with rest breaks)
• People with severe difficulty speaking or understanding language, severe visual problems or neglect, untreated severe depression, or a psychiatric illness that would prevent them from taking part
• People with significant muscle stiffness (spasticity) in the affected arm or hand above a certain level
• People experiencing moderate to severe pain in the affected hand or arm
• People with finger contractures, severely limited hand or wrist movement, active bone fractures, or arthritis causing joint deformity
• People with severe uncontrolled limb movement problems (ataxia or apraxia)
• People with severely reduced sensation across the entire affected arm
• People whose brain signals for imagined movement cannot be detected by the BCI device
• People who have had part of their skull removed (craniectomy), as this may affect how the BCI device fits
• People currently taking part in another interventional research trial
• People living in a nursing home or overseas who may not be able to attend the research site regularly
• People who are pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.