COPD Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with chronic obstructive pulmonary disease (COPD), a long-term lung condition that makes breathing difficult
• People who are currently experiencing a sudden worsening of their COPD where carbon dioxide has built up in the blood and the blood has become more acidic, confirmed by specific blood test results
• People who are over 40 years old

Who may not be able to join:

• People who have asthma
• People whose doctor determines they urgently need a breathing tube inserted right away
• People for whom neither of the two treatments being studied can be physically applied
• People who are not expected to be able to give consent to participate, either straight away or later — for example, due to known memory or thinking problems, dementia, a serious active mental health condition, or significant intellectual disability
• People who already use a breathing support machine at home (such as NIV or CPAP), or who have a known medical reason to use one — for example, sleep apnoea or a condition where obesity causes breathing problems during sleep
• People who are expected to die very soon
• People who have certain other serious conditions that may affect how well the treatments work, including a recent heart attack, fluid on the lungs caused by heart failure, or a large blood clot in the lungs — note that lung infections, which commonly cause COPD flare-ups, are not a reason for exclusion
• People who have other serious conditions that would prevent safe participation, such as very unstable blood pressure requiring medication, severely reduced consciousness, or serious poisoning
• People who have a surgically created opening in the throat for breathing (a tracheostomy)
• People who are already taking part in another clinical trial involving a treatment or intervention
• People who cannot be admitted to the intensive care unit or a closely monitored ward at the participating hospital
• People who have previously stated clearly, verbally or in writing, that they do not want to take part in research
• People whose blood bicarbonate level (a measure of the blood's chemistry) is below 20 mmol/L (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.