Pulmonary Hypertension Trial, Recruiting NCT06090838 Sponsor: Amsterdam UMC, location VUmc Condition: Pulmonary Hypertension
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Pulmonary Hypertension Trial, Recruiting

NCT06090838
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who had an acute blood clot in the lungs (pulmonary embolism) at least 3 months before joining the trial, which was properly treated
  • People who still have ongoing breathing or activity limitations, rated as a level 2 or higher on a standard medical scale (NYHA class ≥2)
  • People who still show significant areas of reduced blood flow in the lungs on imaging scans (at least 3 affected segments)
  • People whose exercise test results show at least 2 signs of reduced exercise capacity that cannot be explained by another condition — such as lower-than-expected oxygen uptake, oxygen delivery, breathing efficiency, or a drop in blood oxygen levels during exercise (confirm with trial site for specific test values)
  • People who have completed at least 8 weeks of a lung rehabilitation program, finishing no more than 2 months before being enrolled in the trial
  • People whose exercise tests were done after completing the rehabilitation program
  • People aged between 18 and 80 years
  • People who score below 5 on a 9-point fitness and frailty scale (meaning they are not considered significantly frail)
  • People who are willing and able to provide written consent to participate
  • People who are currently on, or who restart, a full therapeutic dose of blood-thinning medication before being enrolled

Who may not be able to join:

  • People who have previously had certain procedures to treat blocked lung arteries (balloon pulmonary angioplasty or pulmonary endarterectomy)
  • People who have remaining blood clots that are not suitable for a balloon pulmonary angioplasty procedure
  • People who have significant other serious heart or lung conditions that are expected to affect their survival, exercise ability, or breathing — such as significant coronary heart disease, heart failure, high blood pressure in the lungs, severe chronic lung disease (COPD grade 3 or higher), scarring of the lungs, disabling nerve or muscle disease, or active cancer
  • People who are unable to complete exercise tests
  • People who have an allergy to contrast dye used in medical imaging
  • People whose kidneys are not functioning well enough (a kidney function measure below a certain level — confirm with trial site)
  • People who are pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 0031204444444

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Amsterdam UMC, location VUmc
Registry
ClinicalTrials.gov
Start date
15 June 2023
Est. completion
31 October 2025

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

disease specific quality of life

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov