Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have a close family member (parent, sibling, or child), living or deceased, who has been diagnosed with or probably had Alzheimer's disease that developed later in life
• People who have noticed changes in their own memory and are concerned about those changes
• People who score 26 or higher on a standard memory and thinking test called the Montreal Cognitive Assessment (MoCA)
• People who are willing to give their formal agreement to take part in the study
• People who are able to follow the treatment schedule throughout the study
• People whose medications have been the same for at least 2 months and are not expected to change during the study (if taking any medications)
• People who pass a safety screening questionnaire related to the treatment used in this trial (a type of brain stimulation called TMS)
• People who have a family member, friend, or carer who is able to fill in questionnaires about the participant during the study

Who may not be able to join:

• People who have any metal implants in their head (outside the mouth), such as ear implants, brain stimulators, or aneurysm clips
• People who have, or have had, increased pressure in the brain, which may raise the risk of seizures
• People who have a cardiac pacemaker
• People who have an implanted medication pump
• People who have a central venous line (a type of tube inserted into a large vein)
• People who have a significant heart condition
• People who currently have depression, or have a history of certain mental health conditions including psychotic disorders, bipolar disorder, eating disorders, obsessive compulsive disorder, post-traumatic stress disorder, or a type of dementia other than Alzheimer's disease
• People who have used alcohol or drugs problematically in the last 6 months
• People who have had a stroke or have other known lesions (areas of damage) in the brain
• People who have a personal history of epilepsy
• People who have a family history of epilepsy
• Women who are pregnant or breastfeeding
• People who have had an abnormal brain MRI scan
• People who have significant hearing loss that requires hearing aids
• People who have an untreated thyroid condition (either underactive or overactive thyroid)
• People who have other reasons they cannot safely receive TMS (confirm with trial site)
• People who have unstable medical conditions
• People who have regularly used benzodiazepines (a type of sedative or anxiety medication) or other sleep medications within 2 weeks of being enrolled in the study

Important: Always verify eligibility with the trial site directly before applying.