Crohn's Disease and Colitis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with ulcerative colitis (a type of bowel disease) for at least 3 months, with test results from a camera examination of the bowel and tissue samples that confirm the diagnosis
• People whose ulcerative colitis is considered moderate to severe, based on specific scoring tools that measure symptoms and the appearance of the bowel lining
• People whose condition meets the medical guidelines for treatment with either vedolizumab (a drip-based medication) or upadacitinib (a tablet-based medication)

Who may not be able to join:

• People who are unable to take upadacitinib tablets by mouth or unable to attend regular drip infusions of vedolizumab
• People who show signs of toxic megacolon (a dangerous swelling of the large bowel) at the time of screening
• People who have previously had large portions or all of their large bowel surgically removed, or who have had a stoma (an opening in the abdomen for waste) created due to ulcerative colitis
• People who need bowel surgery because of their ulcerative colitis, or who plan to have any scheduled surgery during the study period
• People with evidence of serious, worsening, or poorly controlled problems affecting the kidneys, liver, blood, hormone system, lungs, mental health, or nervous system
• People who show signs of an active hepatitis B or hepatitis C infection at the time of screening

Important: Always verify eligibility with the trial site directly before applying.