Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For people with knee osteoarthritis (target: 40 participants):
- People aged 45 or older
- People who experience knee pain that is brought on or made worse by activity
- People whose morning knee stiffness either does not occur or lasts no longer than 30 minutes
- People who would rate their knee pain at least 4 out of 10 on a pain scale
- People whose knee pain is their main pain complaint, if they have pain in more than one area
- People who can speak and understand English
For people without pain (target: 20 participants):
- People who do not have any pain-related medical condition
- People who can speak and understand English
Who may not be able to join:
For people with knee osteoarthritis:
- People who have nerve damage or reduced sensation in the wrist, knee, or forearm
- People who use electrically active medical devices, such as a pacemaker
- People who regularly use opioid pain medications
- People who are pregnant
- People who have a serious or uncontrolled ongoing condition affecting the heart, lungs, kidneys, liver, nervous system, metabolism, hormones, digestive system, or who have epilepsy
- People who have rheumatoid arthritis, ankylosing spondylitis, or a neurological condition that would prevent participation in the study procedures
- People who have cognitive impairment
- People who have previously had a knee replacement
- People who are unable to exercise due to severe pain or other symptoms
- People who have had any treatment procedure for their knee pain in the past 3 months
For people without pain:
- People who have experienced any pain episode in the past 3 months, whether from a musculoskeletal injury or any other cause
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Kosaku Aoyagi, PhD, Assistant Professor
Phone: 9157478215
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Changes in pressure pain thresholds (Measure of exercise-induced hypoalgesia); Mechanical temporal summation; Conditioned pain modulation; Knee pain
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.