Phase 4 Crohn's Disease and Colitis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must be willing to take part and have given your written agreement (or have someone legally authorized to do so on your behalf) before any checks are done.
• You have been previously diagnosed with Crohn's disease, ulcerative colitis, or an unclassified form of inflammatory bowel disease, confirmed through medical tests such as a camera exam of the gut, tissue samples, or scans.
• You are 18 years old or older.
• Your bowel disease is currently in remission (well-controlled) without the use of steroids — meaning your symptoms such as bleeding, stool frequency, abdominal pain, and loose stools are at very low levels — and you have not needed steroids for at least the past 8 weeks.
• Your blood test (CRP) and stool test (calprotectin) results show low levels of inflammation at the time of screening.
• You have been receiving infliximab through an intravenous (IV) drip for at least 26 weeks in a row.
• Your IV infliximab dose has stayed the same for at least the past 20 weeks.
• Your average infliximab dose over 8 weeks (based on your two most recent treatments) is more than 8 mg/kg but no more than 22 mg/kg.
• You can speak and read Dutch, French, or English fluently.

Who may not be able to join:

• You are 18 years old or younger.
• You have had certain bowel surgery, such as a pouch operation or a stoma (ostomy bag).
• You are currently taking part in another clinical trial involving an experimental medicine or device.
• You have previously been treated with a subcutaneous (under-the-skin injection) form of infliximab.
• You currently have active fistulas (abnormal tunnels) in the area around the back passage.
• You have a condition called microscopic colitis.

Important: Always verify eligibility with the trial site directly before applying.