Osteoarthritis Trial, Recruiting NCT06122727 Sponsor: Istituto Ortopedico Rizzoli Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT06122727
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 40 to 70 years (inclusive) who are being considered for a primary cemented total knee replacement surgery.
  • People who are willing to participate and are able to attend the required study visits and follow-up appointments.
  • People who have signed the consent form that has been approved by the Ethics Committee.

Who may not be able to join:

  • People who are homeless or whose personal freedom is restricted in some way.
  • People with a health status rating classified as ASA 3 (a medical scoring system used by doctors to assess surgical risk — confirm with trial site).
  • People who have deep vein insufficiency in their legs (poor blood flow through the veins of the lower limbs).
  • People who have a history of erysipelas (a type of skin infection) in their legs.
  • People with neurological conditions (conditions affecting the brain or nerves) or cognitive/psychological disorders.
  • People with a diagnosis of post-traumatic arthritis (joint damage caused by a previous injury).
  • People whose knee has a significant axis deformity (a bowing or misalignment) of more than 10 degrees.
  • People with a personal or family history of deep vein thrombosis (blood clots in the veins) or pulmonary embolism (blood clots in the lungs).
  • People who have previously had a joint replacement or joint fusion surgery on any other joint in the lower limbs (other than the knee being considered for this trial).
  • People who are pregnant.
  • People who have been diagnosed with a rheumatic disease (conditions involving inflammation of the joints or connective tissue, such as rheumatoid arthritis).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 0516366

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Istituto Ortopedico Rizzoli
Registry
ClinicalTrials.gov
Start date
1 March 2023
Est. completion
30 June 2026

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Angle Hip Knee Ankle; Angle Hip Knee Ankle

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov