Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who identify as women
• People who are able to give written consent to participate
• People who can speak, read, and understand English or Spanish
• People who are post-menopausal, including those whose ovaries have been medically suppressed
• People who have been diagnosed with a specific type of advanced or metastatic breast cancer that is hormone receptor-positive (ER+ and/or PR+), regardless of HER-2 status
• People who have started a first or second course of hormone-based therapy combined with a CDK4/6 inhibitor (such as palbociclib, ribociclib, or abemaciclib), with or without certain targeted HER2 therapies, within the past 90 days — previous use of a CDK4/6 inhibitor in an earlier stage of treatment is allowed, and switching between CDK4/6 inhibitors due to side effects or insurance reasons does not disqualify someone, provided enrollment happens within 90 days of starting the relevant treatment (confirm with trial site)
• People who have not regularly done more than 90 minutes of moderate exercise or 45 minutes of vigorous exercise per week for the past 3 months (where "regularly" means at least half the time)
• People who have not regularly done resistance or strength training 2 or more days per week over the past 3 months
• People who have not regularly followed a fasting routine of 12 hours or more overnight for the past 3 months (where "regularly" means at least half the time)
• People whose cancer specialist (medical oncologist) has approved their participation

Who may not be able to join:

• People who are unable to give informed consent
• People who cannot read or understand English or Spanish
• People who require oxygen to breathe
• People with unstable heart disease
• People who require insulin to manage diabetes
• People who are unable to walk 2 blocks without assistance (note: use of a cane does not disqualify someone)
• People who have worked evening, night, or rotating shifts regularly in the past 3 months
• People with a history of a clinically diagnosed eating disorder
• People with unstable spread of cancer to the bones
• People for whom more than 90 days have passed since starting the qualifying hormone therapy and CDK4/6 inhibitor combination in the advanced or metastatic setting
• People with a serious medical or psychiatric condition, or who take medications, that would prevent safe participation in the study activities (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.