Pulmonary Hypertension Trial, Recruiting NCT06129240 Sponsor: Liquidia Technologies, Inc. Condition: Pulmonary Hypertension
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Pulmonary Hypertension Trial, Recruiting

NCT06129240
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Cohort A (Group A):

  • Adults between 18 and 80 years old
  • Have been diagnosed with a specific type of pulmonary hypertension linked to lung disease (called WHO Group 3 PH-ILD), confirmed by a chest CT scan showing widespread lung disease, plus specific pressure measurements taken during a heart procedure (confirm with trial site for exact numbers)
  • Able to walk at least 125 meters (about 410 feet) in 6 minutes

Cohort B (Group B):

  • Adults between 18 and 75 years old
  • Have been diagnosed with the same type of pulmonary hypertension linked to lung disease (WHO Group 3 PH-ILD), confirmed by a chest CT scan and specific heart pressure measurements (confirm with trial site for exact numbers)
  • Already taking a specific inhaled medication called treprostinil at a set dose, but not yet at their treatment goal, and able to switch to a different form of the same medication
  • Able to walk at least 200 meters (about 656 feet) in 6 minutes

Who may not be able to join:

Cohort A (Group A):

  • People whose pulmonary hypertension falls into a different category (WHO Groups 1, 2, 4, or 5)
  • People with a significant history of heart problems on the left side of the heart
  • People currently experiencing a flare-up of their lung disease, or who have an active lung or upper respiratory infection
  • People who have recently started a pulmonary rehabilitation program

Cohort B (Group B):

  • People whose pulmonary hypertension falls into a different category (WHO Groups 1, 2, 4, or 5)
  • People who are unable to increase their dose of inhaled treprostinil beyond a certain level (confirm with trial site for exact amounts)
  • People who have had bronchospasm (sudden tightening of the airways) caused by treprostinil medications
  • People with a history of moderate or severe persistent asthma
  • People with a significant history of heart problems on the left side of the heart
  • People currently experiencing a flare-up of their lung disease, or who have an active lung or upper respiratory infection

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Liquidia Technologies, Inc.
Registry
ClinicalTrials.gov
Start date
28 December 2023
Est. completion
31 July 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Cohort A: Incident of treatment-emergent drug/device-related adverse events and Serious Adverse Events (SAEs); Cohort B: Number of participants with treatment-emergent drug/device-related adverse events and Serious Adverse Events (SAEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov