Alzheimer's Disease Trial, Recruiting NCT06129838 Sponsor: Washington University School of Medicine Condition: Alzheimer's Disease
Back to Alzheimers Disease

Alzheimer's Disease Trial, Recruiting

NCT06129838
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People of any race, male or female, aged 50 years or older
  • People who are able to sign a consent form themselves, or who have a legally authorised representative who can consent on their behalf
  • For the Alzheimer's disease and related dementias (ADRD) group specifically: people with a clinical diagnosis of mild cognitive impairment or early dementia related to ADRD, or people who have been identified through biological markers as having Alzheimer's disease, whether or not they currently have symptoms

Who may not be able to join:

  • People with a known allergy or sensitivity to the study imaging agent [11C]-CS1P1 or its ingredients
  • People for whom PET, CT, or MRI scans would be considered unsafe — for example, those with certain electronic medical devices implanted in their body, or those who cannot lie still for extended periods
  • People with severe claustrophobia (extreme fear of enclosed spaces)
  • People who are currently pregnant or breastfeeding
  • People who are currently receiving radiation therapy
  • People with any condition that the trial doctor believes could increase health risks, limit their ability to complete the study procedures, or affect the reliability of the data collected — for example, kidney or liver failure, or advanced cancer (confirm with trial site)
  • People who, in the last 6 months, have experienced certain serious heart conditions, including significant irregular heartbeats, certain types of heart block, unstable chest pain (angina), or severe heart failure requiring hospitalisation
  • People with moderate to severe anaemia, indicated by a haemoglobin level below 9.9 in both males and females
  • People who have taken part in other research studies involving radioactive agents within the past 12 months, where the combined radiation exposure would exceed the limits set by US federal regulations

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Tammie Benzinger, Washington University School of Medicine

Phone: 314 273 6140

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
5 May 2023
Est. completion
1 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

PET imaging studies of [11C]-CS1P1 in healthy control participants and participants with Alzheimer's Disease and measuring the uptake of [11C]-CS1P1 tracer.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov