Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are over 40 years old
- People who are able to give informed consent (agree to participate after being fully informed)
- People who have had knee pain caused by osteoarthritis for at least 6 months
- People whose knee pain has not improved enough with treatments such as medication, physical therapy, or changing their activity levels, for at least 3 months, and who are seeking a total knee replacement
- People who are considered a candidate for a total knee replacement at Hotel Dieu Hospital
- People who are able to attend all required follow-up visits and complete all parts of the study
Who may not be able to join:
- People who currently have an active infection in or near the affected area
- People who have a condition where the immune system attacks the body, such as rheumatoid arthritis, lupus, multiple sclerosis, or other autoimmune diseases
- People who are currently taking medication that suppresses the immune system
- People who have known blood vessel disease in their legs, or leg symptoms believed to be caused by poor blood circulation (such as pain when walking or pain at rest)
- People who have a blood clotting disorder that cannot be reversed
- People whose kidneys are not functioning well enough, based on a specific blood test result taken within the past 60 days (confirm with trial site)
- People who cannot safely have an MRI scan — for example, due to claustrophobia, or having metal fragments, implants, or prostheses in their body
- People who have had a severe allergic reaction (such as anaphylaxis) to the contrast dye used in CT or MRI scans
- People who are pregnant, or people of childbearing potential who are not currently using a medically accepted form of contraception
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: David Clinkard, MD, Queen's University
Phone: 613-549-6666
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Changes in knee pain/functionality post geniculate artery embolization versus nerve ablation vs sham
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.