Phase 1 Breast Cancer Trial, Recruiting NCT06171607 Sponsor: University of Southern California Condition: Breast Cancer
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Phase 1 Breast Cancer Trial, Recruiting

NCT06171607
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a newly found breast lump that has been rated as BIRADS 4a, 4b, 4c, or 5 on a standard ultrasound and has been recommended for an ultrasound-guided biopsy (confirm with trial site if unsure of your BIRADS rating)
  • People who are 18 years of age or older
  • People who are female

Who may not be able to join:

  • People who have a known condition of high blood pressure in the lungs (pulmonary hypertension), or a known allergic reaction to ultrasound contrast agents (special dyes used during ultrasound scans)
  • People with kidney failure or reduced kidney function — but only if the trial involves a contrast-enhanced scan called CESM
  • People with an allergy to iodine-based contrast dye — but only if the trial involves a CESM scan
  • People whose breast lump measures 1 cm or smaller at its widest point — but only if the trial involves a contrast-enhanced ultrasound scan (CEUS)
  • People who are pregnant, possibly pregnant, or currently breastfeeding
  • People who are currently receiving chemotherapy before surgery (called neoadjuvant chemotherapy)
  • People under 18 years of age
  • People who are 30 years of age or younger — but only if the trial involves a CESM scan
  • People who have a breast lump in the same breast that previously had surgery to remove a cancerous lump (lumpectomy)
  • People who have cancer in the same breast being studied (however, people with cancer in the opposite breast may still be considered eligible)
  • People with a known allergy to a substance called perflutren — but only if the trial involves a CEUS scan
  • People who have previously had a biopsy of the specific breast lump being studied
  • People who have breast implants

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bino A Varghese, PhD, University of Southern California

Phone: 323-865-3205

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
5 November 2020
Est. completion
5 November 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Radiomics-based ML-classifier framework; Performance of radiomics-based ML approach to prevent unnecessary biopsies

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov