Osteoarthritis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a man or woman between 40 and 75 years old (inclusive) with arthritis in one ankle joint, and your doctor has recommended you for a first-time total ankle replacement surgery.
• You are willing and able to attend all required study appointments and follow-up visits.
• You have read and signed the official consent form that has been approved by the Ethics Committee.

Who may not be able to join:

• You are experiencing difficult social circumstances, such as homelessness or restrictions on your personal freedom.
• You have been rated as ASA class 3 or 4, meaning you have serious or severe health conditions that affect your overall fitness for surgery (confirm with trial site).
• You have poor blood flow returning from the veins in your legs (deep vein insufficiency).
• You have a history of a serious skin and tissue infection called erysipelas in your legs.
• You have a neurological condition or a disorder affecting your thinking, memory, or mental health.
• Your ankle has a significant bone or joint misalignment of more than 15 degrees.
• You or a close family member have a history of blood clots in the veins (DVT) or lungs (pulmonary embolism).
• You have previously had joint replacement or joint fusion surgery on another joint in the same or opposite leg (other than the ankle being treated).
• You are pregnant.
• You have a rheumatic disease, such as rheumatoid arthritis.
• Your ankle surgery would require additional procedures beyond the ankle replacement itself.

Important: Always verify eligibility with the trial site directly before applying.