Stroke Trial, Recruiting NCT06194968 Sponsor: The First Affiliated Hospital of Zhengzhou University Condition: Stroke
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Stroke Trial, Recruiting

NCT06194968
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older.
  • People who have been clinically diagnosed with an acute ischemic stroke (a stroke caused by a blockage in blood flow to the brain), confirmed by brain imaging showing a relevant area of damage, or with symptoms lasting more than 24 hours, with a scan ruling out bleeding or non-stroke causes.
  • People experiencing their first stroke, or those who have had a previous stroke but recovered well with little to no lasting disability (as measured by a standard disability scale called the mRS, with a score of 1 or less).
  • People whom the treating doctors have assessed as suitable to receive clot-dissolving medication given through a drip (either urokinase or alteplase).
  • People who are willing to take part voluntarily and sign a consent form — or whose legally authorised representative or relatives can provide consent on their behalf where this is applicable.

Who may not be able to join:

  • People for whom clot-dissolving (thrombolysis) treatment is medically unsuitable, based on contraindications listed in the 2018 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke.
  • Women of childbearing age who are known to be pregnant, are breastfeeding, or who have a positive pregnancy test at the time of admission.
  • People with a known history of drug or controlled substance abuse or addiction in the past year.
  • People with an existing cancer or severe systemic illness where life expectancy is estimated to be less than 90 days.
  • People whose mental illness or cognitive (thinking or memory) difficulties would prevent them from being able to follow the study requirements.
  • People who have taken part in another clinical trial involving a drug or medical device within the 3 months before screening.
  • People whom the treating doctors consider unsuitable for this study for any other reason.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
The First Affiliated Hospital of Zhengzhou University
Registry
ClinicalTrials.gov
Start date
30 December 2023
Est. completion
1 November 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

modified Rankin scale (mRS) 0-2 (good functional outcome) at day 90

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov