Phase 3 Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 75 years old, of any nationality
• People whose general health and ability to carry out daily activities falls within a certain range, as measured by a standard oncology scale called the ECOG scale (scores 0–2, meaning ranging from fully active to capable of limited self-care — confirm with trial site)
• People diagnosed with breast cancer of any subtype, where early-stage patients have not previously had chemotherapy, and advanced-stage patients are starting their first round of chemotherapy and have not had certain pre- or post-surgery chemotherapy for more than 3 months — and where the planned chemotherapy is a specific high-intensity type involving anthracycline with cyclophosphamide (EC or AC) or carboplatin/cisplatin at certain doses
• People with a life expectancy of at least 3 months
• People whose bone marrow, kidney, and liver are functioning well enough as shown by blood tests
• Women who have not yet reached menopause and who are using adequate contraception
• People who have given written consent to participate before joining the trial

Who may not be able to join:

• People who have already received chemotherapy
• People scheduled to receive a lower-intensity type of chemotherapy (non-HEC) on the first treatment day
• People scheduled to receive any chemotherapy on days 2 through 4 after their first high-intensity chemotherapy session
• People who have received or are scheduled to receive radiation therapy to the abdomen, pelvis, head, or neck within one week before the first treatment day, or between days 1 and 5 of the first treatment cycle
• People who have a brain tumour (primary or spread from elsewhere) that is causing nausea or vomiting
• People who are currently experiencing nausea or vomiting
• People with significant existing medical or mental health conditions
• People with known allergies to the study drug, anti-nausea medications, or the steroid dexamethasone
• People with significantly abnormal results on certain blood tests (including platelet count, clotting levels, white blood cell count, and liver and kidney markers)
• People who are pregnant or breastfeeding
• People with an active inflammatory skin condition
• People who have lymphoedema (fluid swelling) in the area of the body where acupuncture would be applied
• People who are afraid of electroacupuncture or who are allergic to stainless steel needles
• People who have received acupuncture treatment for any reason within the 4 weeks before starting chemotherapy
• People currently using medications that prevent nausea or vomiting, such as certain anti-nausea drugs, steroids (unless at very low doses), or sedatives — with some exceptions (confirm with trial site)
• People with certain conditions that may increase the risk of vomiting, such as a bowel blockage, active stomach ulcers, high calcium levels in the blood, or brain metastases causing symptoms
• People with a seizure disorder requiring ongoing anti-seizure medication
• People taking a specific antipsychotic medication called thioridazine on an ongoing basis
• People currently being treated with quinolone-type antibiotics
• People with a history of chronic heavy alcohol use, as determined by the trial investigators
• People with known irregular heart rhythms, uncontrolled heart failure, or a heart attack within the past six months
• People with uncontrolled diabetes, for example those using insulin or diabetes tablets

Important: Always verify eligibility with the trial site directly before applying.