Phase 3 Prostate Cancer Trial, Recruiting NCT06205316 Sponsor: Mayo Clinic Condition: Prostate Cancer
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Phase 3 Prostate Cancer Trial, Recruiting

NCT06205316
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been confirmed by laboratory testing to have prostate adenocarcinoma (a specific type of prostate cancer) at the time of their surgery
  • People whose cancer was found to be at certain stages (T2 through T3b, with specific lymph node and spread classifications) based on their surgical pathology report
  • People whose PSA (a prostate-related protein measured in the blood) was between 0.1 and less than 2.0 ng/mL, tested at least 6 weeks after surgery and within 90 days before joining the trial
  • People with a general health and activity level rated as 0, 1, or 2 on a standard medical scale (confirm with trial site), assessed within 90 days of enrollment
  • People who are able to sign a consent form approved by an ethics review board
  • People who are able to complete all required pre-entry tests within the specified timeframes
  • People who are able to begin treatment (hormone therapy or radiation) within 120 days of registering for the study
  • People who are 18 years of age or older
  • People whose cancer has spread to no more than 5 sites in the body (known as oligometastatic disease)

Who may not be able to join:

  • People who have previously had radiation treatment to the pelvic area
  • People who have previously received hormone therapy (androgen deprivation therapy) for prostate cancer and have a PSA of 0.1 ng/mL or higher
  • People with currently active rectal diverticulitis, Crohn's disease affecting the rectum, or active ulcerative colitis
  • People who have previously had chemotherapy for prostate cancer
  • People with a history of a narrowing of the upper part of the urethra that required a procedure to widen it
  • People with a significant medical, addiction-related, or psychiatric condition that, in the doctor's opinion, would prevent them from completing treatment or follow-up (note: consent through a legal representative is not permitted for this trial)
  • People who have had a heart attack or severe heart failure within the last 6 months
  • People who are currently on an organ transplant waiting list
  • People whose cancer has spread to more than 5 sites in the body

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Carlos E. Vargas, MD, Mayo Clinic

Phone: 855-776-0015

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
22 January 2024
Est. completion
22 January 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of grade 3 or higher genitourinary (GU)/gastrointestinal (GI) radiation treatment-related adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov