Early Phase 1 Pancreatitis Trial, Recruiting NCT06205342 Sponsor: Medical University of South Carolina Condition: Pancreatitis
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Early Phase 1 Pancreatitis Trial, Recruiting

NCT06205342
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 75 years old (any gender)
  • You have been formally diagnosed with chronic pancreatitis
  • You have had ongoing pain from chronic pancreatitis for more than 6 months, whether the pain is constant or comes and goes
  • Your pain score measured by a specific tool called the Izbicki scale is above 30 (the trial team will calculate this)
  • Your opioid pain medication dose has stayed the same for the past 30 days

Who may not be able to join:

  • You have had a sudden, acute flare-up of pancreatitis in the last 30 days
  • You have another chronic pain condition (separate from pancreatitis) that requires you to take opioid pain medication every day
  • You have serious failure of one or more organs that is likely to affect pain-related results within 6 months (confirm with trial site)
  • Your long-term blood sugar control test (HbA1c) shows a result above 10%
  • Certain blood test results fall outside acceptable ranges, including very low white blood cell counts, low hemoglobin, low platelets, abnormal liver values, or high creatinine levels (the trial team will check these)
  • You have been diagnosed with moderate or severe heart failure (New York Heart Association Class 2 or higher)
  • You have or have had lung, blood, or solid organ cancer — other than certain early-stage skin or cervical cancers — within the past 3 years
  • You currently have hepatitis B, hepatitis C, or HIV
  • You currently have any active cancer, except for certain non-melanoma skin cancers
  • You have taken part in another clinical trial involving an experimental drug or device in the past 30 days, or plan to during this study
  • You are planning to have an endoscopy with treatment, surgery, or drainage of a pancreatic structure in the next 6 months
  • You have had pancreatic surgery, a therapeutic endoscopy procedure, or a hospital stay related to pancreatitis in the past 90 days
  • You have had ongoing problems with alcohol or illegal drug use in the past 6 months
  • You currently have an infected fluid collection or area of dead tissue around the pancreas
  • You are pregnant, breastfeeding, or are of childbearing potential and unwilling to use adequate contraception during the study (this applies to male participants with female partners of childbearing potential as well)
  • You are not willing to follow the study plan and attend required assessments

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Hongjun Wang, PhD, Medical University of South Carolina

Phone: 843-792-2813

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Registry
ClinicalTrials.gov
Start date
17 July 2024
Est. completion
1 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Izbicki pain score (M6 vs. Baseline)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov