Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have had a recent stroke affecting the front part of the brain and are receiving a procedure to open a blocked blood vessel within 24 hours (without prior clot-busting medication).
- People who are 18 years of age or older.
- People who had little to no disability in daily life before the stroke started.
- People whose emergency brain scan (CT) shows that the stroke has not damaged a large portion of the brain (a score of 7 or higher on a standard brain scan rating scale).
- People whose emergency blood vessel scan shows a blockage in one of the major arteries supplying the brain (the internal carotid artery or specific segments of the middle cerebral artery).
- People whose advanced brain imaging shows a certain amount of at-risk but potentially salvageable brain tissue — specifically, a damaged core area between 10 mL and 100 mL, with the surrounding at-risk tissue being more than 1.2 times the size of the core.
- People who are willing and able to follow the study procedures, and who (or whose authorised representative) can sign a consent form.
Who may not be able to join:
- People with serious heart, liver, or kidney problems, blood clotting disorders, inability to tolerate surgery, or known allergies to the study drug (Human Urinary Kallidinogenase) or to contrast dye used in imaging scans.
- People whose brain scans show any bleeding in or around the brain, such as a bleeding stroke or blood clots inside the skull.
- People with a history of bleeding in the brain, brain tumours, brain injury, or other existing brain conditions.
- People who regularly take a type of blood pressure medication called ACE inhibitors and are unable to stop taking them.
- People who have had major surgery or a serious physical injury within the past 2 weeks.
- People who are unlikely to be able to follow the study procedures consistently.
- People who are pregnant or breastfeeding.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Qiang Dong, M.D., Huashan Hospital
Phone: 13701747065
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
ASPECT score evaluated using routine CT; Modified Rankin Scale (mRS) score
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.