Phase 4 Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Women between 18 and 70 years old
• People whose breast cancer has been confirmed by tissue testing to be HER-2 positive (a specific protein found on cancer cells), verified by the research centre's pathology department
• People whose cancer has come back or spread to other parts of the body, as confirmed by imaging scans
• People whose cancer returned or spread at least three months after stopping treatment with the drug Trastuzumab
• People who have at least one tumour that can be measured on scans, based on standard medical measurement guidelines
• People with a general health and activity level rated 0–2 on a standard scale used by doctors (confirm with trial site)
• People with an expected life span of at least three months
• People whose major organs (such as heart, liver, and kidneys) are functioning normally
• People whose treating doctor believes they may benefit from the trial
• People who are willing to participate and have signed a consent form

Who may not be able to join:

• People with a confirmed history of drug allergies, or who have had a severe allergic reaction to any ingredient in the study drug
• People in advanced stages of the disease who have already received systemic (whole-body) treatment
• People with a history of serious heart conditions, such as heart failure, unstable chest pain, irregular heartbeat, or heart attack
• People with serious lung diseases, such as scarring of the lung tissue, lung inflammation, or other significant lung conditions
• People currently experiencing severe liver disease, such as active or severe hepatitis or problems with blood clotting; people who test positive for certain hepatitis B markers must have a very low level of the hepatitis B virus in their blood to be considered (confirm with trial site)
• People with other ongoing illnesses or conditions that could affect their safety or interfere with the trial, such as an active or uncontrolled infection, or active liver or gallbladder disease requiring antiviral treatment
• People with another active invasive cancer (including a second breast cancer) that could affect how results are measured
• People who have had major surgery or have not yet recovered from a serious illness in the four weeks before joining the trial
• People whose treating doctor considers them unsuitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.