Breast Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have signed a written consent form agreeing to take part in the trial
• Women aged 18 or older
• People diagnosed with a specific type of early-stage (non-metastatic) breast cancer called triple-negative breast cancer (TNBC), meaning the cancer tests negative for certain hormone receptors and a protein called HER2, and who have already had imaging scans to check whether the cancer has spread
• People who have had surgery aimed at removing all of the cancer, where that surgery took place between 3 and 9 months before joining the trial, and who have been receiving any recommended follow-up (adjuvant) treatment for at least 12 weeks before joining
• People whose cancer is considered high-risk, meaning at least one of the following applies: the cancer did not fully disappear after chemotherapy given before surgery; the cancer was at an advanced local stage (stage IIB or III) and no pre-surgery chemotherapy was given; or the cancer has come back in the same breast area after a previous TNBC that was treated with curative intent
• People who show no signs of the cancer returning locally or spreading to other parts of the body, as assessed by their doctor
• People who have a general health status that allows them to carry out everyday activities without significant limitation (confirm with trial site what the specific health score threshold means for eligibility)
• People for whom a stored tumour tissue sample of sufficient size and quality is available
• People who are able to follow the requirements of the trial
• People who have health insurance coverage

Who may not be able to join:

• People with another serious uncontrolled illness, abnormal test results, or any other medical condition that the investigator believes would interfere with the trial
• Male participants
• People with a mental health condition or altered mental state that the investigator believes would prevent them from giving meaningful informed consent
• People who would have difficulty taking part in trial procedures for geographic, social, or psychological reasons
• People who are currently in custody or under legal guardianship
• People who have had another type of cancer in the past, unless it was a skin cancer (basal cell carcinoma), a non-invasive cancer treated with curative intent, or an early-stage cancer (stage I or II) treated with curative intent with no signs of active disease in the last five years
• People whose cancer has already spread to other parts of the body (metastatic relapse) before any molecular sign of relapse is detected through blood testing — this applies specifically to the second stage of the trial involving a particular blood test result (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.