Phase 2 Osteoarthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are male or female and older than 18 years of age.
• People who have been diagnosed with thumb base (CMC) joint arthritis at stage I, II, or III, confirmed by X-ray.
• People whose thumb pain is rated 5 or higher on a standard 10-point pain scale.
• People who are willing and able to give written consent and follow the study requirements.
• People who are willing to avoid using opioid pain medications and over-the-counter pain medications during the study, and to keep a log if they do use them.

Who may not be able to join:

• People who are pregnant, breastfeeding, planning to become pregnant during the study, or unwilling to use birth control during the study.
• People with any condition or abnormality that, in the trial doctor's opinion, could affect their safety or the reliability of study results.
• People with a known or suspected allergy to the study drug (TA-ER) or its ingredients, including triamcinolone acetonide.
• People with stage IV CMC joint arthritis, as these cases typically involve severe joint damage and are more likely to require surgery.
• People who have been diagnosed with rheumatoid arthritis, septic arthritis, gout-related arthritis, psoriatic arthritis, thumb joint fluid buildup, DeQuervain's disease, or trigger thumb.
• People who have previously had surgery to reconstruct the affected thumb joint.
• People with serious, uncontrolled long-term medical conditions.
• People who have received hyaluronan or platelet-rich plasma (PRP) injections into the affected thumb joint within the past 6 months.
• People who have received a steroid injection into the affected thumb joint within the past 3 months.

Important: Always verify eligibility with the trial site directly before applying.