Phase 2 COPD Trial, Recruiting NCT06273072 Sponsor: Johns Hopkins University Condition: COPD
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Phase 2 COPD Trial, Recruiting

NCT06273072
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with asthma by a doctor and are currently taking regular asthma medication to manage it
  • People whose asthma is not well-controlled, meaning their asthma control test (ACT) score is below 20, or they have had at least one asthma flare-up in the past 12 months that required steroid treatment
  • People who are overweight or obese, with a body mass index (BMI) of 25 or higher
  • People who are 18 years of age or older

Who may not be able to join:

  • People who are currently pregnant, planning to become pregnant in the next 6 months, or currently breastfeeding
  • People who have had a serious heart condition, heart attack, or stroke within the last 6 months
  • People who have another long-term lung condition, such as COPD, bronchiectasis, or scarring of the lungs
  • People who currently smoke, or former smokers with a heavy smoking history (20 pack-years or more) (confirm with trial site)
  • People with significant kidney disease, where the kidneys are not functioning above a certain level (confirm with trial site)
  • People who drink heavily — generally 8 or more drinks per week for women, or 15 or more drinks per week for men
  • People with liver disease, or whose liver function blood tests show results more than twice the normal level
  • People with low red blood cell levels (anaemia), based on specific blood test thresholds for men and women (confirm with trial site)
  • People currently taking GLP-1 medications (such as those used for weight loss, for example semaglutide)
  • People with diabetes, including those with a specific blood sugar marker above a certain level, or those taking metformin or other diabetes medications
  • People already taking part in another clinical trial (participation in observational studies is permitted)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Meredith C McCormack, M.D., M.H.S., Johns Hopkins University

Phone: 410-955-1530

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
9 December 2024
Est. completion
30 September 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of completed telemedicine visits; Adherence to study drug; Retention rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov