Phase 2 Breast Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Women between 18 and 70 years old who have not yet received any treatment for breast cancer
• People with a good general health status, able to carry out normal daily activities with little or no limitation (based on a standard health scoring system)
• People whose breast cancer has been confirmed by a lab test (biopsy) as invasive breast cancer at stage II or IIIA
• People whose cancer is hormone receptor (HR) positive and HER-2 positive
• People whose blood counts, liver function, kidney function, and heart function all fall within acceptable ranges as measured by blood tests and a heart ultrasound (confirm with trial site for specific values)
• Women who have not gone through menopause or had surgical sterilization must agree to use effective contraception during treatment and for at least 7 months after the last dose
• People who are willing to volunteer for the study and sign a consent form

Who may not be able to join:

• People whose breast cancer has spread to other parts of the body (stage IV or metastatic)
• People diagnosed with inflammatory breast cancer
• People who have previously received any anti-cancer treatment or radiation therapy for any cancer, with the exception of certain previously cured skin cancers or cervical cancer in situ
• People who are currently taking part in another clinical trial that involves anti-cancer treatments, including hormone therapy, bone-strengthening therapy, or immunotherapy
• People who had a major surgery unrelated to breast cancer within 4 weeks before joining, or who have not fully recovered from such a surgery
• People who have a history of significant lung conditions, such as lung scarring, lung inflammation, or radiation-related lung damage requiring treatment, or who are found to have such conditions during screening
• People with serious heart conditions, including a history of heart failure, uncontrolled irregular heartbeat, chest pain requiring medication, significant heart valve disease, evidence of a previous major heart attack on an ECG, or poorly controlled high blood pressure (above 180/100 mmHg)
• People who are unable to swallow or who have a bowel obstruction or other condition that would prevent them from taking or absorbing the study medication
• People with a known allergy to any of the ingredients in the study drugs, a history of immune system disorders (including HIV), other immune deficiency conditions, or a history of organ transplant
• Women who are pregnant, breastfeeding, or who have a positive pregnancy test at the start of the study, or women of childbearing age who are unwilling to use effective contraception during the trial and for 7 months after the last dose
• People with serious other health conditions that might interfere with the planned treatment, or anyone the study doctor considers unsuitable for the trial for any other reason

Important: Always verify eligibility with the trial site directly before applying.