Crohn's Disease and Colitis Trial, Recruiting NCT06294925 Sponsor: Pfizer Condition: Crohn's Disease and Colitis
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Crohn's Disease and Colitis Trial, Recruiting

NCT06294925
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 64 years old (of any gender) at the start of the study.
  • People who have a confirmed diagnosis of ulcerative colitis and whose doctor has independently decided to prescribe them etrasimod for moderately to severely active ulcerative colitis, in line with the medication's approved use.
  • People who have read, understood, and signed a consent form agreeing to take part in the study.

Who may not be able to join:

  • People whose symptoms suggest they may have Crohn's disease rather than ulcerative colitis.
  • People whose doctor believes they are likely to need hospitalisation for a medical or surgical procedure related to their ulcerative colitis (such as removal of the colon) within the next 12 weeks.
  • People currently showing signs of acute severe ulcerative colitis, a sudden serious flare (fulminant colitis), or a life-threatening complication called toxic megacolon.
  • People who already have a stoma (a surgical opening in the abdomen) or who have a planned ulcerative colitis surgery that would require hospitalisation.
  • People who have previously taken etrasimod at any time, including in a previous clinical trial involving this medication.
  • People currently taking certain other medications alongside etrasimod, including methotrexate, azathioprine, mercaptopurine, or tioguanine; or advanced treatments such as biologic therapies (TNF, integrin, or cytokine blockers), JAK inhibitors (filgotinib, tofacitinib, or upadacitinib), or any other medication in the same class as etrasimod (S1P receptor modulators).
  • People who do not own a digital device with internet access, are unwilling to complete health questionnaires on such a device, or are unable to use the questionnaire tool provided.
  • People who work at the trial site or are employed by Pfizer and are directly involved in running the study, as well as their immediate family members.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Pfizer CT.gov Call Center, Pfizer

Phone: 1-800-718-1021

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
8 May 2024
Est. completion
30 June 2026

Where this trial is recruiting

🇨🇦 Canada 🇩🇪 Germany 🇬🇧 United Kingdom

Primary endpoints

Proportion of patients with symptomatic remission; Proportion of patients with symptomatic remission

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov