Phase 1 Ovarian Cancer Trial, Recruiting NCT06297525 Sponsor: Step Pharma, SAS Condition: Ovarian Cancer
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Phase 1 Ovarian Cancer Trial, Recruiting

NCT06297525
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have signed and dated a consent form and are able to follow the study procedures.
  • Adults aged 18 or older.
  • People with advanced cancer that cannot be cured by currently available treatments and requires systemic (whole-body) treatment.
  • People whose cancer type has been confirmed through a tissue biopsy or lab analysis.
  • People who have tumor tissue available that can be tested for specific biological markers.
  • People whose cancer can be measured on scans (specific measurement standards apply depending on which part of the trial is involved).
  • People who are well enough to carry out basic daily activities, based on a standard health performance scale (confirm with trial site).
  • People whose doctor estimates they have a life expectancy of more than 3 months.
  • People whose bone marrow, liver, kidneys, and blood clotting are functioning at adequate levels.
  • People whose side effects from previous cancer treatments have mostly resolved or returned to near-normal levels before joining (hair loss is an exception).

Who may not be able to join:

  • People who are pregnant or breastfeeding, or people of childbearing potential or males who are unwilling to follow the trial's contraception requirements.
  • People with active or symptomatic cancer that has spread to the brain or spinal cord, or who have a history of spinal cord compression.
  • People who have had another separate cancer that was active within the last 2 years.
  • People who have had radiation therapy within 2 weeks before starting the trial treatment.
  • People who have received systemic cancer treatments, antibody-based therapies, or other experimental treatments within 4 weeks before joining (or within a certain time based on how long the previous treatment stays in the body, whichever is sooner).
  • People with serious ongoing illnesses that are not well controlled.
  • People with a weakened immune system who are at higher risk of unusual infections, or who have had such an infection in the past 12 months.
  • People with a known active or long-term hepatitis B infection, or an active hepatitis C infection.
  • People whose heart electrical activity shows a specific abnormality (a prolonged QTcF interval above 470 milliseconds) on a screening heart tracing (ECG).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Maureen Higgins, Step Pharma

Phone: +33 1 86 26 43 56

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Step Pharma, SAS
Registry
ClinicalTrials.gov
Start date
2 August 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇫🇷 France 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Safety and Tolerability

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov