Phase 2 Ovarian Cancer Trial, Recruiting NCT06315491 Sponsor: Cybrexa Therapeutics Condition: Ovarian Cancer
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Phase 2 Ovarian Cancer Trial, Recruiting

NCT06315491
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed (confirmed by a lab test of tissue or cells) with a specific type of high-grade ovarian, fallopian tube, or primary peritoneal cancer.
  • Your cancer has stopped responding to platinum-based chemotherapy (a common cancer treatment), meaning it either kept growing during treatment or came back within about 6 months of your last platinum treatment — or you have progressed after a second course of platinum-based treatment.
  • You have received no more than 2 additional treatment regimens beyond platinum-based chemotherapy (note: maintenance therapies like PARP inhibitors or bevacizumab do not count as separate regimens).
  • You are 18 years of age or older at the time of signing the consent form.
  • Your cancer can be measured on a scan (according to a standard medical measurement system called RECIST 1.1).
  • You are willing and able to give written consent to participate.
  • You are generally able to carry out daily activities with little or no limitation (confirm with trial site).
  • Your liver, kidneys, blood, lungs, and blood-clotting functions are all working well enough (confirm with trial site).

Who may not be able to join:

  • You have received chemotherapy, a biologic treatment, an experimental treatment, or radiation therapy within the last 3 weeks before starting the trial drug.
  • You are currently taking any other cancer treatment or experimental drug.
  • You have another serious or significant ongoing illness or medical condition (confirm with trial site).
  • You currently have an active HIV infection.
  • You currently have an active hepatitis B or hepatitis C infection.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Michael Needle, MD, Cybrexa Therapeutics

Phone: 860-717-2731

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Cybrexa Therapeutics
Registry
ClinicalTrials.gov
Start date
25 September 2024
Est. completion
1 October 2025

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percentage of Subjects With Complete Response (CR) or Partial Response (PR) [Objective Response Rate (ORR)]

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov