Stroke Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have had a single stroke on one side of the brain, occurring in adulthood.
• People whose stroke affected either the outer layers of the brain (cortex) or the deeper nerve pathways (such as the internal capsule or corona radiata).
• People who had either a blocked-artery stroke (ischemic) or a bleeding stroke (hemorrhagic).
• People whose stroke happened more than 6 months ago.
• People who are able to walk 10 metres, with or without a cane, walker, brace, or other walking aid.
• People who have weakness on one side of the body as a result of their stroke.
• People who tend not to use their weaker leg even though some ability to move it remains (confirm with trial site on how this is assessed).
• People who have no medical reasons preventing them from exercising safely, such as recent heart attack, uncontrolled heart rhythm problems, unstable chest pain, uncontrolled high blood pressure, or severe joint or muscle conditions that would interfere with pedalling.
• People aged 18 or older.
• People who are able to commit to 27 visits to the research lab (including assessment sessions and 24 training sessions).

Who may not be able to join:

• People who have had more than one stroke that caused lasting effects or showed up on brain imaging (note: a mini-stroke, or TIA, that left no lasting damage does not automatically exclude someone).
• People whose stroke primarily affected the cerebellum (the part of the brain that coordinates balance and movement) or the basal ganglia (areas deep in the brain involved in movement control).
• People with dementia or other cognitive difficulties that interfere with learning or with giving informed consent.
• People with communication difficulties, such as trouble understanding spoken or written language, that would prevent safe participation (note: people who have difficulty speaking but can communicate in another way are not automatically excluded).
• People with joint, muscle, or bone problems that would interfere with pedalling.
• People with heart or cardiovascular conditions that make exercise unsafe.
• People who are unable to walk 10 metres overground, or cannot do so safely.
• People with any other neurological condition or brain injury besides stroke, such as cerebral palsy, epilepsy, Parkinson's disease, multiple sclerosis, brain tumour, head trauma, or diabetic nerve damage.
• People with any other condition that the research team determines could make participation unsafe or could affect the study results.
• People who do not meet all of the inclusion criteria listed above.

Important: Always verify eligibility with the trial site directly before applying.