Pulmonary Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Heart Failure group:
- You are older than 18 years
- You are willing and able to sign a consent form to participate
- Your heart's pumping strength (the amount of blood pumped out with each beat) is below 50%
- You have been diagnosed with heart failure for more than 6 months
- You are currently taking water pills (a type of medication called a loop diuretic) to manage fluid
- Your doctor has already recommended a procedure to measure pressures inside your heart (right heart catheterisation)
Control group (people without heart failure):
- You are older than 18 years
- You are willing and able to sign a consent form to participate
- You are a patient at a specific medical centre in Prague (IKEM) attending for a procedure such as closing a small hole in the heart (PFO closure), a heart rhythm treatment (arrhythmia ablation), or a heart pressure measurement — or you are attending for non-invasive tests only
Who may not be able to join:
Heart Failure group:
- Your heart condition is currently unstable and requires strong medicines to keep it pumping
- Your kidneys are not working well enough (confirm with trial site for exact level)
- You have recently had a heart attack or acute coronary event
- Your heart is pumping too much blood (higher than normal output) (confirm with trial site)
- You have a type of high blood pressure in the lungs that is not related to heart failure (types I, III, or IV)
- You currently have an active infection
- You are having significant difficulty breathing due to a breathing problem
- You have a large build-up of fluid around your lungs
- You have a serious lung condition such as treated COPD, asthma, or a known scarring/thickening disease of the lungs
Control group:
- You have high blood pressure in the lungs, shown on an ultrasound scan of your heart
- You have had a blood clot in your lungs within the last year
- An ultrasound of your heart shows that either side of your heart is not pumping properly
- You have treated asthma, COPD, or a known scarring/thickening disease of the lungs
- You have significant difficulty doing everyday physical activities due to breathlessness or fatigue (confirm with trial site for exact level)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Vojtech Melenovsky, Institute for Clinical and Experimental Medicine
Phone: 420 236055190
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
biomarker of pulmonary vasculopathy in HF; CT characteristics of pulmonary vasculopathy in HF; CT characteristics of presence of heart failure
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.