Breast Cancer Trial, Recruiting NCT06334354 Sponsor: Memorial Sloan Kettering Cancer Center Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT06334354
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

All participants:

  • People who identify as female, based on their medical records or self-report
  • People who are currently between the ages of 60 and 80
  • People who have access to a computer and internet connection
  • People who score below 11 on a short memory and thinking test called the Blessed Orientation-Memory-Concentration Test (BOMC) (confirm with trial site)
  • People who, if currently taking medications that affect mood or mental health (such as antidepressants or anti-anxiety medications), have been on a stable dose for at least two months before joining
  • People who speak English fluently and can hold a reasonable conversation in English, as confirmed by trial staff

Breast cancer survivors (in addition to the above):

  • People with a history of stage 0 to 3 breast cancer that was first diagnosed between the ages of 50 and 60
  • People who currently have no signs of active cancer (known as "no evidence of disease")

People with no cancer history (control group, in addition to the general criteria above):

  • People who have never had breast cancer

Who may not be able to join:

All participants:

  • People who have been diagnosed with a condition that affects brain function, such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, dementia, or seizure disorders
  • People who have had a stroke or a head injury that caused lasting brain changes, ongoing thinking or memory difficulties affecting daily life, or required cognitive rehabilitation
  • People who have been diagnosed with certain serious mental health conditions, including schizophrenia-related disorders, bipolar disorder, schizotypal personality disorder, or substance use disorder
  • People with vision or hearing problems severe enough to prevent them from completing the study assessments, even with glasses or hearing aids
  • People who take the medications methotrexate or rituximab for rheumatoid arthritis, psoriasis, or Crohn's disease, or cyclophosphamide for lupus
  • People who are already taking part in a conflicting research study that involves overlapping brain and thinking assessments (specifically study MSK 18-294)

Breast cancer survivors:

  • People whose breast cancer has come back (recurrence)
  • People who have had any other type of cancer, except non-melanoma skin cancer (a second breast cancer also makes someone ineligible)
  • People whose breast cancer was treated with surgery only, with no other treatments

People with no cancer history (control group):

  • People who have previously been treated with radiation, chemotherapy, tamoxifen, or aromatase inhibitors
  • People who have had any history of cancer, except non-melanoma skin cancer

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: James Root, PhD, Memorial Sloan Kettering Cancer Center

Phone: 646-888-0035

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
10 May 2024
Est. completion
31 August 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

examine cognitive effects

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov