Phase 2 Vasculitis Trial, Recruiting NCT06335888 Sponsor: Insel Gruppe AG, University Hospital Bern Condition: Vasculitis
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Phase 2 Vasculitis Trial, Recruiting

NCT06335888
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 50 years old or older and your doctor suspects you may have Giant Cell Arteritis (GCA), a condition causing inflammation of the arteries
  • If you are a woman who could become pregnant, you must have a negative pregnancy blood test at the first visit
  • You are able to understand what the study involves and are willing to sign a consent form agreeing to take part
  • You are willing and able to follow all the steps and procedures required by the study

Who may not be able to join:

  • You have low levels of folate (a type of B vitamin) in your body
  • You are pregnant, breastfeeding, or planning to become pregnant during the study or within 30 days after the last dose of the study medicine
  • You are currently taking certain medicines that lower folic acid levels, such as methotrexate, pemetrexed, or raltitrexed
  • You have received a glucose (sugar) drip or nutrition through a drip within 6 hours before the scan
  • Your blood sugar level is too high at the time of the scan (confirm with trial site)
  • You are unable to stay inside the PET/CT scanning machine for the full length of the scan
  • You are unable to lie still for about 45 minutes
  • You are unable to avoid eating or drinking (other than water) for 6 hours before receiving the imaging substance used in the scan
  • You have had a PET scan within the last 60 days before the study begins
  • You have taken vitamin supplements containing more than 1mg per day of folic acid within 48 hours before your scan
  • You have a known allergy or sensitivity to folic acid
  • You are a close family member, employee, or dependent of one of the researchers running the trial
  • You are currently taking part in another clinical trial involving an experimental medicine, or have done so within the 7 days before joining this study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Britta Maurer, Department of Rheumatology and Immunology, Inselspital, University of Bern, Bern, Switzerland

Phone: +41 31 63 2 7229

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Insel Gruppe AG, University Hospital Bern
Registry
ClinicalTrials.gov
Start date
3 February 2025
Est. completion
1 May 2029

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

Specificity of the GCA-diagnosis at the patient level

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov