Schizophrenia Trial, Recruiting NCT06336382 Sponsor: Jeremy Koppel Condition: Schizophrenia
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Schizophrenia Trial, Recruiting

NCT06336382
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 65 and 85 years old (male or female)
  • You have been diagnosed with a late-onset psychotic disorder, specifically either "very late-onset schizophrenia-like psychosis" or "delusional disorder" (confirm with trial site)
  • You have a caregiver who can provide information about your history and take part in some assessments
  • You have scored 0 or 0.5 on a standard memory and thinking assessment called the Clinical Dementia Rating scale (confirm with trial site)
  • You scored 24 or higher on a standard thinking and memory test called the Mini-Mental State Examination
  • Your memory function is within a normal range based on a standard memory test, adjusted for your level of education
  • You are able to hear certain sound frequencies in both ears during a hearing test (hearing aids are allowed)

Who may not be able to join:

  • You have certain other mental health or medical conditions, including bipolar disorder, schizoaffective disorder, active major depression, insulin-dependent type 2 diabetes, a history of heart or cardiovascular disease, epilepsy, a serious brain injury with more than 15 minutes of unconsciousness, Parkinson's disease or other movement disorders, stroke, an autoimmune disease affecting the brain or nervous system, a substance use disorder, or current delirium (confirm with trial site)
  • You have a significant neurological condition identified by a doctor
  • You score above 4 on a scale used to assess blood flow-related brain changes (confirm with trial site)
  • You have had issues with alcohol or drug dependency in the last 5 years
  • You have metal implants in your body, such as a pacemaker, ear implants, or bullet/shrapnel fragments
  • You are unable to lie flat for approximately one hour
  • You are unable to hear the required sound frequencies in both ears during a hearing test, even with hearing aids

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jeremy Koppel, MD, Northwell Health

Phone: 516-562-3492

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Jeremy Koppel
Registry
ClinicalTrials.gov
Start date
16 February 2024
Est. completion
31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Quantification of neurofibrillary tangle pathology in subjects via PET [18F]PI-2620 radiotracer uptake.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov