Phase 2 Breast Cancer Trial, Recruiting NCT06340230 Sponsor: Shengjing Hospital Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Recruiting

NCT06340230
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women aged 18 to 75 years
  • People whose breast cancer has been confirmed by a tissue sample (biopsy) to be a type called HR-positive and HER2-low invasive breast cancer
  • People who have not yet received any treatment for their breast cancer and whose cancer is at stage II or III
  • People who are relatively active and able to carry out everyday activities, as measured by a standard health scoring system (a score of 0 or 1 on the ECOG scale)
  • People whose major organs (such as the liver, kidneys, and heart) are functioning at a good level
  • People who are willing to participate voluntarily, sign a consent form, follow the trial requirements, and attend follow-up visits

Who may not be able to join:

  • People who have previously received any cancer treatment, such as chemotherapy, radiotherapy, targeted therapy, or hormone therapy
  • People who are currently receiving any other cancer treatment at the same time as this trial
  • People who have cancer in both breasts, inflammatory breast cancer, or a type where the cancer cannot be detected in the breast itself (occult breast cancer)
  • People whose breast cancer has spread to other parts of the body (stage IV)
  • People whose cancer has not been confirmed through a tissue sample (biopsy)
  • People who have had any other type of cancer in the past 5 years, except for certain fully treated cancers such as early-stage cervical cancer or a specific type of skin cancer (non-melanoma skin cancer) (confirm with trial site)
  • People who have taken part in another clinical drug trial within the 4 weeks before joining this trial
  • People with a known allergy to any of the ingredients in the treatments used in this trial
  • People with a history of a weakened immune system
  • People with significant heart or blood vessel problems
  • People with known or suspected lung disease affecting the tissue between the air sacs (interstitial lung disease)
  • People with active hepatitis (liver infection) or liver cirrhosis (liver scarring)
  • People with a known tendency to bleed or form blood clots, whether inherited or developed over time
  • People with a history of neurological (brain or nerve) or psychiatric (mental health) conditions

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Caigang Liu, MD, Shengjing Hospital

Phone: 86-18940256668

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shengjing Hospital
Registry
ClinicalTrials.gov
Start date
23 August 2024
Est. completion
28 February 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Total pathological complete response (tpCR: ypT0-is/ypN0)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov